Weight loss (GLP-1)
Missed Doses, Side Effects, and Restarting After a Break
Missed Dose Protocol
- If there are more than 48 hours until your next scheduled dose: Take the missed dose now, then resume your normal weekly schedule.
- If there are less than 48 hours until your next dose: Skip the missed dose and resume normally.
- Never double-dose under any circumstances.
Common Side Effects
GLP-1 medications affect your digestive system, especially early in treatment. Common side effects include:
- Nausea and vomiting
- Diarrhea or constipation
- Reduced appetite
- Bloating and heartburn
- Headache, fatigue, or dizziness
Side effects typically decrease as your body adjusts during dose escalation. If side effects are significant, your clinician may reduce your dose by approximately 10 units and increase more slowly.
Restarting After a Break
| Time Off Medication | What to Do |
|---|---|
| Less than 2 weeks | Resume at your current dose |
| 2–4 weeks off | Restart one dose level lower |
| More than 30 days | Restart from the beginning (starting dose) |
Restarting too aggressively after a break significantly increases side effects.
Information only, not medical advice. Treatment decisions are made by your licensed provider. Last updated September 29, 2026.