Maintenance Dosing #
Once you’ve reached your goal weight or a BMI of 24, your clinician will work with you to taper to the lowest dose that maintains your results.
- Semaglutide: Taper down to 0.22 mg or as low as a 0.125 mg microdose
- Tirzepatide: Taper down to 2.2 mg or as low as a 1.0 mg microdose
Most patients find a maintenance dose that preserves their results without the need to remain at a high therapeutic dose.
Storing Your Medication #
- Refrigerate between 36–46°F (2–8°C)
- One dose may remain unrefrigerated (below 86°F) for up to 21 days
- Never freeze GLP-1 medications
- Keep out of direct sunlight
Additional Health Benefits of GLP-1 Therapy #
Beyond weight loss, research shows GLP-1 medications provide significant metabolic and systemic health benefits:
- Lowers HbA1c (blood sugar control)
- Reduces cardiovascular risk
- Improves kidney function
- Benefits obstructive sleep apnea
- Reduces systemic inflammation
- Early neurological research suggests potential reduction in dementia risk