PrescribedRX provides clinician-supervised prescriptions for oral PDE5 inhibitors, the most commonly used and well-researched class of ED medications.
Available Medications #
- Sildenafil (generic Viagra)
- Tadalafil (generic Cialis)
How They Work #
PDE5 inhibitors relax the smooth muscle tissue in the penis, allowing increased blood flow during sexual stimulation. They do not cause an automatic erection — sexual stimulation is required.
How to Take Them #
- Take 30–60 minutes before sexual activity
- Tadalafil at a low daily dose (2.5–5 mg) may be taken every day instead of on-demand, providing continuous readiness
Important Safety Information #
- Do not combine with nitrate medications (e.g., nitroglycerin for heart conditions). This combination can cause a dangerous drop in blood pressure.
- Alpha Blocker medications (often used for blood pressure or prostate issues) should not be combined with PDE5 inhibitors without explicit guidance from your provider.
- If you are unsure whether your current medications interact, message your clinician through the portal before taking.
